neworleanscajundancers.com

After over 15 years of research, the scientists finally managed to identify the genes that cause Alzheimer’s disease.

Three genes are clusterin, complement receptor 1 (CR1), and PICALM, who allegedly is a type of gene most commonly found in 90 percent of cases of Alzheimer’s. Identification of genes was performed by two groups of scientists in Wales, England, and France.

“If we can eliminate the three genes that have a damaging effect this, we can reduce the risk of Alzheimer’s by 20 percent,” said Julie Williams, a professor of genetic Neuropsychological from Britain’s Cardiff University.

Other genes are also associated with a disease that causes dementia in old age is apolipoprotein E (ApoE) were identified in 1993 since the experts knew that the decline of brain function associated with genetic factors.

In recent studies done by Professor Williams, it performs a scan of the genetic map of the 16,000 people from eight countries. Finally managed to identify two genes, called clusterin and PICALM that increase the risk of Alzheimer’s.

The second study conducted by Philippe Amouyel and colleagues from the Pasteur de Lille in France, a 6000 study of Alzheimer’s patients and 9000 healthy people in France, Belgium, Finland, Italy, and Spain. The researchers also identified a third gene clusterin and called CR1.

Although these three genes are relatively found in all patients, Amouyel said that rather difficult to calculate the risk of Alzheimer’s disease with genes. He also stressed that not known, any combination of genes and other environmental factors of what causes Alzheimer’s.

Experts say, clusterin may cause Alzheimer’s risk 10 percent, PICALM about 9 percent, and 4 percent of CR1. When added together, the risk is estimated to be 20-25 percent.

Three variations of this gene is also associated with early symptoms of Alzheimer’s disease revealed the emergence of the family. Therefore, by identifying these genes, scientists will more easily identify the cause of illness and create drugs to fight it.

Memory decline

Alzheimer’s is a disease that causes deterioration in memory and thinking power of the death of nerve cells quickly. It is estimated there are about 500,000 cases of Alzheimer’s disease in Indonesia.

Alzheimer’s symptoms vary in each person, but can be characterized by the occurrence of memory loss, such as forgetting names, forgetting where to put things, disruption of daily activities, changes in mood and behavior, disorientation, and often stray. At a certain point, people with Alzheimer’s does not remember anything else about yourself, family, and environment.

They are at risk of Alzheimer’s are the elderly (more than 60 years), had a family history of Alzheimer’s affected, stroke, heart disorders, diabetes, and head injury / brain.

Alzheimer’s drugs currently available are kolinesterase inhibitors. Drug to improve memory and behavioral disorders pressing, as well as improved quality of life.