The cause of Alzheimer’s Genes
Written by on September 7, 2009 – 3:50 pm -After over 15 years of research, the scientists finally managed to identify the genes that cause Alzheimer’s disease.
Three genes are clusterin, complement receptor 1 (CR1), and PICALM, who allegedly is a type of gene most commonly found in 90 percent of cases of Alzheimer’s. Identification of genes was performed by two groups of scientists in Wales, England, and France.
“If we can eliminate the three genes that have a damaging effect this, we can reduce the risk of Alzheimer’s by 20 percent,” said Julie Williams, a professor of genetic Neuropsychological from Britain’s Cardiff University.
Other genes are also associated with a disease that causes dementia in old age is apolipoprotein E (ApoE) were identified in 1993 since the experts knew that the decline of brain function associated with genetic factors.
In recent studies done by Professor Williams, it performs a scan of the genetic map of the 16,000 people from eight countries. Finally managed to identify two genes, called clusterin and PICALM that increase the risk of Alzheimer’s.
The second study conducted by Philippe Amouyel and colleagues from the Pasteur de Lille in France, a 6000 study of Alzheimer’s patients and 9000 healthy people in France, Belgium, Finland, Italy, and Spain. The researchers also identified a third gene clusterin and called CR1.
Although these three genes are relatively found in all patients, Amouyel said that rather difficult to calculate the risk of Alzheimer’s disease with genes. He also stressed that not known, any combination of genes and other environmental factors of what causes Alzheimer’s.
Experts say, clusterin may cause Alzheimer’s risk 10 percent, PICALM about 9 percent, and 4 percent of CR1. When added together, the risk is estimated to be 20-25 percent.
Three variations of this gene is also associated with early symptoms of Alzheimer’s disease revealed the emergence of the family. Therefore, by identifying these genes, scientists will more easily identify the cause of illness and create drugs to fight it.
Memory decline
Alzheimer’s is a disease that causes deterioration in memory and thinking power of the death of nerve cells quickly. It is estimated there are about 500,000 cases of Alzheimer’s disease in Indonesia.
Alzheimer’s symptoms vary in each person, but can be characterized by the occurrence of memory loss, such as forgetting names, forgetting where to put things, disruption of daily activities, changes in mood and behavior, disorientation, and often stray. At a certain point, people with Alzheimer’s does not remember anything else about yourself, family, and environment.
They are at risk of Alzheimer’s are the elderly (more than 60 years), had a family history of Alzheimer’s affected, stroke, heart disorders, diabetes, and head injury / brain.
Alzheimer’s drugs currently available are kolinesterase inhibitors. Drug to improve memory and behavioral disorders pressing, as well as improved quality of life.
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The cause of Alzheimer’s Genes
September 7th, 2009After over 15 years of research, the scientists finally managed to identify the genes that cause Alzheimer’s disease.
Three genes are clusterin, complement receptor 1 (CR1), and PICALM, who allegedly is a type of gene most commonly found in 90 percent of cases of Alzheimer’s. Identification of genes was performed by two groups of scientists in Wales, England, and France.
“If we can eliminate the three genes that have a damaging effect this, we can reduce the risk of Alzheimer’s by 20 percent,” said Julie Williams, a professor of genetic Neuropsychological from Britain’s Cardiff University.
Other genes are also associated with a disease that causes dementia in old age is apolipoprotein E (ApoE) were identified in 1993 since the experts knew that the decline of brain function associated with genetic factors.
In recent studies done by Professor Williams, it performs a scan of the genetic map of the 16,000 people from eight countries. Finally managed to identify two genes, called clusterin and PICALM that increase the risk of Alzheimer’s.
The second study conducted by Philippe Amouyel and colleagues from the Pasteur de Lille in France, a 6000 study of Alzheimer’s patients and 9000 healthy people in France, Belgium, Finland, Italy, and Spain. The researchers also identified a third gene clusterin and called CR1.
Although these three genes are relatively found in all patients, Amouyel said that rather difficult to calculate the risk of Alzheimer’s disease with genes. He also stressed that not known, any combination of genes and other environmental factors of what causes Alzheimer’s.
Experts say, clusterin may cause Alzheimer’s risk 10 percent, PICALM about 9 percent, and 4 percent of CR1. When added together, the risk is estimated to be 20-25 percent.
Three variations of this gene is also associated with early symptoms of Alzheimer’s disease revealed the emergence of the family. Therefore, by identifying these genes, scientists will more easily identify the cause of illness and create drugs to fight it.
Memory decline
Alzheimer’s is a disease that causes deterioration in memory and thinking power of the death of nerve cells quickly. It is estimated there are about 500,000 cases of Alzheimer’s disease in Indonesia.
Alzheimer’s symptoms vary in each person, but can be characterized by the occurrence of memory loss, such as forgetting names, forgetting where to put things, disruption of daily activities, changes in mood and behavior, disorientation, and often stray. At a certain point, people with Alzheimer’s does not remember anything else about yourself, family, and environment.
They are at risk of Alzheimer’s are the elderly (more than 60 years), had a family history of Alzheimer’s affected, stroke, heart disorders, diabetes, and head injury / brain.
Alzheimer’s drugs currently available are kolinesterase inhibitors. Drug to improve memory and behavioral disorders pressing, as well as improved quality of life.
diet and Sports kick out Obesity
September 19th, 2008
Risk died at the young age of obesity reach 50-100 percent. Obesity is also associated with many diseases such as heart disease, type 2 diabetes, coronary artery disease, high blood pressure, kidney stones, irregular menstruation, infertility and cancer risk (in women such as cervical cancer, and breast egg; In men, prostate cancer and intestine).
Obesity is also frequently associated with discrimination and prejudice that causes people who are overweight to feel inferior and do not have a quality life.
Dr. Ayuthinee Singhakowinta, Chairman of the Diabetes and Metabolic Center in Phyathai Hospital, Bangkok explains, “so successfully manage your weight and body health, you should change your eating habits and lifestyle through exercise. Try starting with simple movements and live everyday life with the active. Crash diet intensive or excessive exercise will not work. ”
Weight loss program for those who have obesity should be initiated and monitored by a doctor or nutritionist. If you are obese, there is a possibility that person also has other health problems such as diabetes and hypertension.
“Consult with your doctor to make sure that you are healthy enough to start a proper diet and exercise to design a good schedule. Normally, exercise to lose weight is at least 30 minutes 3 times a week, humility fat diet and high in fiber and medicine,” Dr. Ayuthinee explained .
Consuming food in the house is a good way to start a weight reduction program. It’s also important to drink lots of water, because water is the fuel that is essential for the body and facilitate digestion.
If you are afraid to workout at the gym, start by doing the movements at home. Stay away from the sofa. Walk around the house. Encourage family members to participate, so feel motivated to exercise. When it reached a comfortable, increase your exercise routine, with cardio, weight training to lose fat, build muscle and get healthy body.
Soybean can Reduce Number of Sperm
September 6th, 2008
A man is considered infertile if she has more than 20 million sperm per millimeter of semen fluid. In order quantity of sperm is maintained, should reduce the prospective father soy consumption.
Research conducted on 99 men with fertility problems showed, those who eat foods made from soy every day, decreased sperm count.
This is caused by chemical compounds called isoflavones in the soy. Isoflavones similar to the hormone estrogen. Increasing the amount of estrogen will make the body fat percentage increased (that’s why women have higher body fat). In fact, excess weight will lead to reduced fertility.
In addition, soybean is also known to reduce the absorption of zinc by the body. For men who are planning a pregnancy, zinc is necessary to increase the number of sperm and testosterone hormone levels.
However, it does not mean all the food made from soybeans should be avoided. What is important is to keep the amount of soy intake was not excessive. The reason, a number of studies that examine the link between soy and fertility showed decreased sperm counts when soybeans are consumed in excessive amounts.
For example, in a study of mice showed that consumption of soy in a low number (approximately 2mg/kg body weight) for 90 days, did not cause a reduction of sperm. Only when the dose increased to 20 mg / kg or 100 mg / kg, a reduction.
Fortunately, levels of soy in the diet is not too high. For example, 1 cup of soy milk contains 30 mg, 1 / 2 cup soy nuts contains 47 mg, tempeh about 37 mg, 20 mg and know. So, if your weight approximately 79 pounds, the new reduction in sperm count occurs when you consume 1600 to 8000 milligrams of soy.
